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On Thursday 5 June 2025, Luxembourg's Ministry of Health and Social Security announced the publication of the 2025 European and national drug reports.

The 30th edition of the European Drug Report, published by the European Union Drugs Agency (EUDA), and the 2025 National Drug Report (Rapport national sur les drogues - RELIS), prepared by the Luxembourg National Focal Point of the EUDA and published by Luxembourg's Health Directorate, provide an in-depth analysis of the drug situation in Europe and Luxembourg.

The European report, based on data from 29 countries (EU plus Norway and Turkey), highlights rapid and complex changes in drug markets, characterised by:

  • an increased supply of psychoactive substances, with more than 1,000 substances monitored by the EU Early Warning System, including 47 newly detected in 2024;
  • the emergence of new powerful opioids, such as nitazenes, causing cases of serious poisoning and death;
  • a shift in the cannabis market, with a high THC concentration and the spread of new products, such as semi-synthetic cannabinoids;
  • injection drug use remains a major health issue, with more than 500,000 users and several reported HIV outbreaks, particularly linked to stimulants.

According to the ministry, these findings call for strengthened prevention, treatment and monitoring systems across Europe.

The 2025 RELIS national report highlights the main trends observed in Luxembourg, notably:

  • cannabis remains the most widely consumed substance, followed by cocaine and ecstasy / MDMA. Since July 2023, the domestic use of cannabis has been authorised within a strictly regulated framework. A preliminary assessment indicated that 14.6% of adults had used cannabis in the twelve months preceding the study, and 11.5% of users had started growing it at home;
  • among young people aged fifteen to 34, 32.7% have used cannabis in their lifetime. Use is more common among men;
  • polydrug use is common in party settings, confirmed by the 2024 national web survey on drugs, with 87.1% of respondents reporting having combined several substances;
  • the use of harm reduction services continues to grow, with more than 109,000 contacts recorded in 2023;
  • overdose deaths remain stable (nine in 2023) and well below the European average;
  • wastewater analyses reveal the regular presence of cannabis, cocaine and MDMA in all monitored areas, with notable peaks on weekends for MDMA.

The ministry noted that these results are part of a national policy based on public health, human rights and harm reduction, driven in particular by the national drug action plan for 2020 to 2024 and the national mental health plan for 2024 to 2028.

Luxembourg's Minister of Health and Social Security, Martine Deprez, stated: "These reports confirm the relevance of our balanced approach, while highlighting the need to continuously adapt our prevention, treatment and harm reduction programmes, particularly in the face of changing drug use. It is essential to continually strengthen prevention efforts, optimise treatment options and consolidate support measures for vulnerable populations."